Durham, North Carolina, USA We are looking for Associate Principal AI Scientists eager to utilize their expertise in these advanced technologies to revolutionize our drug development processes. In the Pharmaceutical Technology and Development (PT&D) department, you will be a key player in transforming molecules into groundbreaking medical treatments. Your role involves contributing data science expertise into cross functional global pharmaceutical development projects in support of transforming the way we deliver medicines to patients. You'll play a pivotal role in shaping our AI strategy and driving the co-development of sophisticated HITL multi-agent systems. We are hiring two candidates for this position and the roles will be based at our dynamic site in Durham (USA). Essential skills/Experience: Min Bachelor´s degree in computer science, data science, artificial intelligence, machine learning or related fields. At least 3 years of experience in Deep Learning and ML Excellent coding skills in languages such as Python, R. Hands-on industrial experience designing multi-agent patterns, digital twins and experience with agentic AI design patterns, reinforcement learning. Extensive industrial experience with AI and ML frameworks like TensorFlow, PyTorch, Hands-on experience with GenAI orchestration frameworks such as LangGraph, CrewAI Hands-on experience with reinforcement learning libraries such as OpenAI Gym, Ray RLlib, or Stable Baselines. Hands-on industrial experience with applied machine learning domains such as deep learning, NLP, GenAI. Desirable skills/experience: Contributions to open-source projects. If you meet these criteria, please highlight merged GitHub PRs in your application. Strong publication record in the field of AI. Experience designing multi-agent systems in the pharmaceutical sector. Experience delivering machine learning projects with applications in pharmaceutical development, chemical engineering or chemistry. Experience with one or more of the following applied machine learning domains such as transfer learning, federated learning, few/zero shot learning, meta learning, explainable AI.

Columbus, Ohio, United States Job Title: Python Developer Location: Columbus, OH (5 Days Onsite) Python, REST API, TDD, no-SQL,AWS Lambda, SNS/SQS, Terraform, API Gateway, ReactJS Note - Candidate must have banking domain experience and more than 4 years of onsite experience. Python Rest API TDD NoSql AWS Lambda Reactjs

REMOTE, REMOTE This is a FULLY REMOTE-WORLDWIDE position ActivePrime is a Silicon Valley Tech company As a senior software engineer, you'll join a team tackling genuinely hard problems: distributed data processing at enterprise scale, complex deduplication algorithms, and systems that need to handle billions of records without breaking. The kind of challenges that require actual engineering thinking, not just tutorial-level code. Ready to tackle complex engineering challenges that impact how the world's largest companies manage their data? Who we are NOT looking for *Agencies *People who are looking for a side “hustle” or are starting their own business *Anyone with less than 8 years of experience If you are a fit for this position, please start your Cover Letter with I AM A SENIOR BACK END PYTHON ENGINEER WITH 8+ YEARS OF EXPERIENCE in all CAPS To be considered pls fill out this form https://forms.clickup.com/2257368/f/24wer-69717/12MWQYCOXQEFIYE71Y Required Skills: *Very proficient with Linux at the terminal level *Test-driven development (TDD) and pytest proficiency *7+ years Python experience *Polars experience *PostgreSQL expertise: schema design, optimization, advanced queries *Familiarity with, and adherence to, PEP guidelines and Python coding standards *RESTful API development and design best practices *Scalable architecture design for high-volume data environments *Security practices and vulnerability prevention *Bug identification and resolution with local testing *Thoughtful development centered around performance, deeply optimized code, and proper code organization *Git version control with branching strategies *English fluency (written/verbal) *Previous experience working for a US-based company.

REMOTE, REMOTE The Role We're seeking a versatile DevOps Engineer with Python language skills, to help scale our infrastructure and operations. This is a "wear many hats" position perfect for someone who thrives in a fast-paced, distributed environment and enjoys building systems that grow with the business. What You'll Do *Maintain and Evolve existing AWS infrastructure for Production and Development Environments. *Develop Automation and Purpose specific applications and Integrations. *Assist with and eventually lead the provisioning system and software release process. *Develop internal tools for employees and partners using our stack (Python, FastAPI, nicegui, PostgreSQL, Vue.js, NiceGUI, Ansible, among other tools). *Manage security policies and help with customer security compliance. *Support our remote-first culture through robust, reliable systems. What We're Looking For *Strong experience in Python development (Libraries, and Services, not just Backend API) *Experience delivering Python Modules across different environments. *Strong experience with AWS infrastructure management, configuration, deployment and monitoring. *Capacity of identifying problems and proposing solutions. *Proven ability to work independently in a remote environment. *Excellent async communication skills and self-management. *Experience building scalable systems from the ground up. *Comfortable with security best practices and compliance requirements. *Adaptability to wear multiple hats and tackle diverse challenges. *We release often, including the weekend. You must be available to work then. What you will need *AWS Dashboard (and CLI) experience *Python language experience *Linux environment experience *(Nice to have) Salesforce Admin/Dev Experience If you are ready to help a growing SaaS company scale please start your cover letter with “ I AM A VERSATILE DEVOPS ENGINEER” We'd love to hear from you. To be considered please fill out the click up form https://forms.clickup.com/2257368/f/24wer-68877/ON1CTQHI8FXGJURL5V

Remote, United States What We’re Building PJMF is building a suite of AI-enabled tools that will serve as the intelligence layer for modern philanthropy. Every year, foundations and corporate funders deploy hundreds of billions of dollars toward humanity's most pressing challenges—yet they do so using systems designed for compliance, not insight. Program officers spend more time reformatting documents and reconciling spreadsheets than learning from their portfolios or deepening relationships with grant partners. Grant Guardian, PJMF’s existing product, already helps hundreds of foundations use AI to streamline their financial due diligence workflows. The next step is a product that will place AI at the center of strategic philanthropy by automatically distilling grant applications into actionable insights, identifying patterns across thousands of grants, generating board materials in minutes, and lowering barriers for historically excluded organizations through features like proposal feedback and translation. About the role: We are seeking a self-driven Junior DevOps Engineer to contribute to the development, deployment, and maintenance of data and AI products that support positive social impact around the world. You will support the maintenance of the cloud infrastructure that powers our AI and data products, while contributing to the full-stack applications built on top of it. You will also work directly with nonprofit partners, helping them understand and adopt the tools we build. We are a small team. We work in short cycles and collaborate across disciplines. In this role, you will contribute directly to cloud-based applications that bring AI outputs into real use. This is an early-career, growth-oriented DevOps role designed for engineers who are building foundational experience in cloud infrastructure, automation, and deployment systems. The role operates under the guidance of senior engineers and progressively assumes greater responsibility as skills and confidence develop. How You’ll Make An Impact: Cloud infrastructure and operations. Maintain and improve our AWS environments using infrastructure-as-code. This includes VPC configuration, IAM policies, secrets management, logging, backups, and cost controls. Application development. Write frontend and backend production code for shared platform services and internal tooling. Our stack includes primarily Go, Python, JavaScript, and React. CI/CD and automation. Contribute to deployment pipelines using GitHub Actions. Automate testing, container builds, releases, and operational workflows like environment provisioning and dependency updates. Containerization and platform support. Support our Docker-based deployment platform, including build workflows, deployment strategies, and autoscaling. Observability and incident response. Implement and maintain metrics, centralized logging, alerting, and dashboards. Participate in incident response under the direction of senior engineers. Developer experience. Build and maintain internal documentation, service templates, and local development tooling that help the team move faster and debug with confidence. Partner collaboration. Work directly with nonprofit partners to support their adoption of our tools. You will translate technical concepts clearly, listen to how partners experience what we build, and bring that feedback into the product cycle. This is recurring, meaningful work, not occasional. Participate in stretch assignments and special projects in service of our broader strategic priorities. What you need to be successful: Education: Bachelor’s degree in Computer Science, Software Engineering, Information Systems, or a related technical field is preferred. Equivalent practical experience may be considered; however, candidates with formal academic training in software or infrastructure-related disciplines are strongly encouraged. Development Experience: 1-3 years of experience in a DevOps, infrastructure, or full-stack engineering role. Programming: Working proficiency in Python or Go is strongly preferred. Experience contributing to production codebases is preferred. Cloud experience: Hands-on experience deploying or supporting production systems on AWS or a comparable cloud platform. Pipeline experience: Experience building and maintaining CI/CD pipelines using modern tooling (e.g., GitHub Actions, etc), source control (GitHub), issue tracking (Jira) and best practices. Infrastructure: Familiarity with relational databases (e.g., PostgreSQL, MySQL) is required. Exposure to containerization tools (e.g., Docker) and Infrastructure as Code (e.g., Terraform) is also expected. Team Collaboration & Communication: Ability to work effectively in a small, virtual, fast-moving team. Communicate clearly in writing and conversation, document work thoughtfully, and demonstrate growing technical judgment when balancing short-term delivery needs with longer-term system considerations. Work eligibility: Applicants must be authorized to work for any employer in the U.S. (No visa sponsorship available) Exposure We Value: Observability experience: Exposure to monitoring, logging, and alerting systems and participating in incident response or on-call rotations. Systems Fundamentals: Basic understanding of networking, system reliability, and security fundamentals Security Fundamentals: Awareness of basic security best practices and an interest in learning how infrastructure security is maintained. Cloud cost & sustainability: Interest in learning how teams monitor infrastructure costs and system efficiency.

Warsaw (fully remote), Poland Lead Python Backend Engineer We’re looking for Python backend engineers interested in team management to work on a trustless supercluster of performance-proofed GPU-enabled sandboxed docker container runners controlled by truly decentralized algorithms (not just PAXOS or RAFT). Wow, that was a mouthful... If you found it interesting, join Reef Technologies and lead a team of senior engineers who tackle complex technical challenges. With us, you’ll work on your own terms: Contribute from wherever you like—we are fully remote but like to stay in sync, so we’re currently hiring in EMEA/APAC. Set your own time commitment, as long as it’s at least 30h per week See how we work in our handbook: github.com/reef-technologies/handbook Influence the way we operate through our Sociocracy 3.0 decision-making process Salary on a B2B contract: 75–90 USD or 300–380 PLN per hour, or 12600–15120 USD or 48000–60800 PLN a month if you work 40 hours per week (most of us work a bit less) Flexible work schedule (as measured with a time tracker) We automatically adjust rates based on inflation twice a year We're looking for someone with 2+ years of team management and 5+ years of programming experience (including at least a year with Python, open source and significant personal projects do count).

London, UK We're building the future of Revenue Management. AI agents that give short-term rental operators and independent hotels more money for less effort. We integrate directly with Booking.com, Airbnb, and PMS platforms via deep private API connections. The role: This is a flexible Hybrid role in London. You'll be the second engineering hire, working directly alongside Martin. Everything is on the table: backend systems, React frontend, Chrome extension, data pipelines, agent orchestration, and prompt engineering. You'll ship full features end-to-end, not tickets. We ship fast using Claude Code and AI-assisted development daily. If you're already running multiple PRs in parallel with AI tools, you'll feel right at home. What we offer: £80K–£90K base salary plus up to 1% equity (DOE). This is a founding role, you'll have real ownership of the product and the company. You'll shape technical direction, product decisions, and company culture from the ground floor. If you want to build something real with a small team that's already winning customers and growing fast, where your code ships to production the same day and your decisions shape the company then let's talk. What we're looking for: Previous startup or founder experience, you've built something from zero and know what that demands. Very strong Python (Django/Celery) and React. Comfortable across the full stack, backend, frontend, infra, data. AI agent development, prompt engineering, or data pipeline experience is a strong plus. You need to be based in London or able to come to our Canary Wharf office 2 days a week. We can't sponsor visas. Stack: Django, Celery, PostgreSQL, React, Chrome Extensions, Claude Code.

Suitland, MD, United States LightFront is seeking a Senior Python & SAS Developer (Data Modernization) to support a long-term Census contract. This role will focus on modernizing legacy federal statistical and survey processing workflows by translating existing logic into scalable Python-based solutions using tools such as pandas, PySpark, and modern data architecture patterns. This is a backend/data modernization role, not a traditional web application role. The developer will support legacy system analysis, backend data processing, database logic optimization, ETL and batch workflows, and cloud-based processing patterns. The work requires someone who is comfortable stepping into established systems, understanding how existing workflows operate, and carefully translating that logic into cleaner, more maintainable solutions without disrupting current operations. This role will be hired initially as a 1099 contractor under LightFront, a joint venture between Illumen Group and Spatial Front, Inc. (SFI), with the potential to convert to full-time employment in the new fiscal year. The role is remote after onboarding, but the selected candidate must report to the Census office in Maryland to retrieve equipment and complete PIV-related onboarding. If the candidate is not local, reimbursable travel will be coordinated after onboarding begins. Clearance / eligibility: Candidates must be U.S. Citizens due to federal contract requirements and must be able to obtain a Public Trust clearance. The clearance process typically takes 6–8 weeks, and candidates must be comfortable with that process and timeline before moving forward. The selected candidate will also need to report to the Census office in Maryland for equipment and PIV pickup after onboarding has started. Travel costs will be reimbursed for non-local candidates. The ideal candidate will have a strong Python background, with at least 4 years of experience in data processing, backend systems, or similar technical environments. This role requires someone who has worked with legacy systems and can translate existing business or data logic into Python-based solutions using tools such as pandas, PySpark, or similar libraries. Candidates should be comfortable working through unclear, messy, or long-standing workflows where the first step is understanding the current logic before rewriting anything. Candidates should also have at least 4 years of database experience, including writing, refactoring, or optimizing stored procedures, backend logic, and complex SQL. Experience with PostgreSQL, PL/pgSQL, Oracle PL/SQL, or similar database environments is important. The role also requires experience with data pipelines, batch processing, ETL workflows, job orchestration, troubleshooting, and performance tuning. AWS experience is also needed, ideally with services such as Lambda, SQS, SNS, IAM, or similar cloud services used in backend or data workflow environments. Linux experience is required, as the role will involve working in Linux-based development and processing environments. Experience with serverless architecture, Docker, Kubernetes, PySpark, R, or hands-on Base SAS production workflows is helpful, but not required. The strongest fit will be someone who has worked with legacy data systems, can translate existing logic rather than only build new features, is comfortable operating in less structured environments, and can balance support for older systems with modern Python, database, and cloud-based workflows.